Severity Level
Conditions
Any metastatic cancer or Stage III or above cancer based on TNM classification, where all treatment modalities have failed and been exhausted and where no other therapies are available and where progression of the cancer can be identified.
1
2
Advanced cancer classified as Stage III or above based on TNM classification.
Advanced cancer classified as Stage II based on TNM classification.
Carcinoma in situ of the breast requiring the removal of the entire breast (total mastectomy).
Cancer classified as Stage I based on TNM classification requiring the removal of the entire breast (total mastectomy).
3
Prostate cancer where the tumour is described histologically as TNM Classification T2 or greater.
Malignant melanoma of Clark level 3 or above; or more than 2mm Breslow thickness; or showing evidence of ulceration.
Carcinoma in situ (Tis) with organ removal. Tumours showing the malignant changes of carcinoma in situ or which are histologically described as pre-malignant, resulting directly in the removal of the entire organ.
Carcinoma in situ of the breast requiring any of the following:
– Breast conserving surgery (lumpectomy, quadrantectomy, segmental mastectomy) and radiotherapy; or
– Breast conserving surgery and chemotherapy and/or immunotherapy.
4
Cancer classified as Stage I based on TNM classification.
Prostate cancer which is histologically described as both TNM Classification T1 and Gleason score of 5 or less, requiring major treatment (including but not limited to prostatectomy, radiotherapy, chemotherapy, or immunotherapy).
Prostate cancer where the tumour is described histologically as TNM Classification T1 and has a Gleason score of 6 or greater.
Malignant melanoma of Clark level 2; or of less than or equal to 2mm and greater than 1mm Breslow thickness.
Cancer of the urinary bladder – Stage Ta.
Carcinoma in situ (Tis) - equivalent of ”In Situ” summary staging. The presence of
malignant/cancerous cells at a stage of development such that they have not spread into surrounding healthy tissue. The tumour must be classified as Tis according to the TNM Classification or FIGO Stage 0.
5
Cervical, vaginal or prostatic intraepithelial neoplasia (dysplasia) with histology showing CIN-3, VIN-3 or PIN-3.
Malignant melanoma of Clark level 1 or melanoma in situ; or of less than 1mm Breslow thickness.
Prostate cancer where the tumour is described histologically as TNM Classification T1 and has a Gleason score of 5 or less.
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1106 AL-PC version 7 Effective 12 May 2026
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